Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530239 | 0.87 | KMT2A (0.56) | KMT2AGAAMEN1MAPTRECQL | |
| SCHEMBL3525480 | 0.82 | KDM4E (0.53) | KMT2AGAAMEN1MAPTKDM4E | |
| SCHEMBL3525856 | 0.73 | AR (0.50) | KMT2AGAAMEN1MAPTRECQL | |
| SCHEMBL4076521 | 0.70 | KMT2A (0.57) | KMT2AGAAMEN1MAPTRECQL | |
| SCHEMBL4078988 | 0.70 | GAA (0.55) | KMT2AGAAMEN1MAPTRECQL | |
| SCHEMBL4088247 | 0.69 | KDM4E (0.53) | KMT2AGAAMEN1MAPTKDM4E | |
| SCHEMBL4088254 | 0.69 | KDM4E (0.53) | KMT2AGAAMEN1MAPTKDM4E | |
| SCHEMBL4086306 | 0.68 | AR (0.55) | KMT2AGAAMEN1MAPTRECQL | |
| SCHEMBL4795202 | 0.67 | AR (0.54) | KMT2AGAAMEN1MAPTRECQL | |
| SCHEMBL4081973 | 0.67 | AR (0.51) | KMT2AGAAMEN1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |