Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B4GALT1 | P15291 | 4/20 | 0.33 |
| ▸ | GSTA2 | P09210 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM1 | P09488 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4087677 | 0.77 | B4GALT1 (0.35) | B4GALT1GSTA2GSTP1GSTM1NT5E | |
| SCHEMBL4084072 | 0.76 | NT5E (0.36) | NT5EMEN1KMT2A | |
| SCHEMBL4087682 | 0.76 | B4GALT1 (0.33) | B4GALT1GSTA2GSTP1GSTM1NT5E | |
| SCHEMBL4078234 | 0.69 | B4GALT1 (0.35) | B4GALT1GSTA2GSTP1GSTM1NT5E | |
| SCHEMBL711087 | 0.68 | — | — | |
| SCHEMBL4078237 | 0.68 | B4GALT1 (0.33) | B4GALT1GSTA2GSTP1GSTM1NT5E | |
| SCHEMBL707764 | 0.64 | TDP1 (0.36) | TDP1NT5E | |
| SCHEMBL4074795 | 0.62 | MEN1 (0.33) | B4GALT1MEN1KMT2A | |
| SCHEMBL705462 | 0.62 | P2RY2 (0.30) | — | |
| SCHEMBL24637959 | 0.62 | P2RY6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |