⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23187 | 0.76 | — | — | |
| SCHEMBL4398751 | 0.75 | — | — | |
| SCHEMBL4682863 | 0.73 | — | — | |
| SCHEMBL755487 | 0.72 | KMT2A (0.39) | — | |
| SCHEMBL93393 | 0.72 | KMT2A (0.39) | — | |
| SCHEMBL4837194 | 0.72 | KMT2A (0.39) | — | |
| SCHEMBL2528459 | 0.71 | — | — | |
| SCHEMBL6910342 | 0.69 | KMT2A (0.37) | — | |
| SCHEMBL9566006 | 0.69 | KMT2A (0.37) | — | |
| SCHEMBL21405194 | 0.69 | KMT2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732259-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20180223278-A1 | Functionally-Modified Oligonucleotides And Subunits Thereof | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-08-09 | — | — | US | disclosed |
| US-10017763-B2 | dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups | SAREPTA THERAPEUTICS, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20180170876-A1 | NOVEL HISTONE DEACETYLASE INHIBITORS | KARUS THERAPEUTICS LIMITED (GB) | 2018-06-21 | — | — | US | disclosed |
| US-20180092938-A1 | OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-04-05 | — | — | US | disclosed |
| US-20180086750-A1 | NOVEL HISTONE DEACETYLASE INHIBITORS AND THEIR USE IN THERAPY | KARUS THERAPEUTICS LIMITED (GB) | 2018-03-29 | — | — | US | disclosed |
| US-9862685-B2 | Histone deacetylase inhibitors | KARUS THERAPEUTICS LIMITED (GB) | 2018-01-09 | — | — | US | disclosed |
| US-9862946-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2018-01-09 | — | — | US | disclosed |
| US-9833468-B2 | Methods for treating progeroid laminopathies using oligonucleotide analogues targeting human LMNA | SAREPTA THERAPEUTICS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170313712-A1 | DIHETEROARYL HISTONE DEACETYLASE INHIBITORS AND THEIR USE IN THERAPY | KARUS THERAPEUTICS LIMITED (GB) | 2017-11-02 | — | — | US | disclosed |
| US-7250514-B1 | Histone deacetylase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2007-07-31 | — | — | US | disclosed |
| US-7169801-B2 | Histone deacetylase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169801-B2 | Histone deacetylase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1280419-A4 | FURFURYL PROPYL DISULFIDE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME | BUSH BOAKE ALLEN INC (US) | 2005-01-19 | — | — | EP | disclosed |
| US-20040266769-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2004-12-30 | — | — | US | disclosed |
| US-6824805-B2 | ADMIXING INGESTIBLE VEHICLE (MEAT, DAIRY, AND BEVERAGE PRODUCTS) WITH ORGANOLEPTIC PURIFIED FURFURYL PROPYL DISULFIDE FORMED BY REACTING SODIUM FURFURYLTHIOLATE WITH SODIUM PROPYLTHIOSULFATE | BUSH BOAKE ALLEN LTD. | 2004-11-30 | — | — | US | disclosed |
| EP-1280419-A1 | FURFURYL PROPYL DISULFIDE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME | Bush Boake Allen Inc. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-20020110628-A1 | Furfuryl propyl disulfide as a flavoring agent and methods for preparing and using same | BUSH BOAKE ALLEN INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2001084959-A1 | FURFURYL PROPYL DISULFIDE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME | BUSH BOAKE ALLEN INC. (US) | 2001-11-15 | — | — | WO | disclosed |
| US-3985907-A | Novel 3-furyl beta oxoalkyl sulfides, processes for producing same and methods for using same for altering the organoleptic properties of foodstuffs | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-10-12 | — | — | US | disclosed |