SCHEMBL4089141

SCHEMBL4089141

FC(F)(F)c1ccc(N(c2ccc3ccc4c(N(c5ccc(C(F)(F)F)cc5)c5cccc6c5oc5ccccc56)ccc5ccc2c3c54)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP1B1 Q16678 2/20 0.35
CYP2E1 P05181 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C8 P10632 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2A6 P11509 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP4B1 P13584 1/20 0.35
CYP2B6 P20813 1/20 0.35
CYP3A5 P20815 1/20 0.35
CYP2A7 P20853 1/20 0.35
CYP3A7 P24462 1/20 0.35
CYP2F1 P24903 1/20 0.35
CYP2C18 P33260 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP2J2 P51589 1/20 0.35
CYP4F2 P78329 1/20 0.35
CYP4F8 P98187 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10354392 0.95 KDM4E (0.32) CYP1A1CYP1A2CYP1B1CYP2E1CYP3A4
SCHEMBL17413327 0.93 VKORC1 (0.35) CYP1A1CYP1A2CYP1B1CYP2E1CYP3A4
SCHEMBL16421378 0.89 CYP1A1 (0.34) CYP1A1CYP1A2CYP1B1
SCHEMBL23278353 0.89 MEN1 (0.31) CYP2D6CYP2C19MEN1KMT2AKEAP1
SCHEMBL18798596 0.87 MEN1 (0.33) CYP1A1CYP1A2CYP1B1POLBMEN1
SCHEMBL18798576 0.87 ALOX5 (0.34) CYP1A2CYP2C19JAK2ZAP70SYK
SCHEMBL2515170 0.87 ALOX5 (0.34) CYP1A2CYP2C19JAK2ZAP70SYK
SCHEMBL4089097 0.87 MEN1 (0.30) CYP2C19MEN1KMT2A
SCHEMBL24425492 0.87 ERBB2 (0.31) CYP1A2CYP2C19MEN1KMT2A
SCHEMBL24425460 0.87 MEN1 (0.30) CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301175-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20220223793-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2022-07-14 US disclosed
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-01-27 US disclosed
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2021-06-01 US disclosed
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-08-13 US disclosed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US disclosed
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 US disclosed
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 US disclosed
US-9978948-B2 Ink composition, organic electroluminescence element, and electronic apparatus JOLED INC. (JP) 2018-05-22 US disclosed
US-9978948-B2 Ink composition, organic electroluminescence element, and electronic apparatus JOLED INC. (JP) 2018-05-22 US disclosed
US-9166179-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2015-10-20 US disclosed
US-9166179-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2015-10-20 US disclosed
US-20140061622-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20130153878-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-06-20 US disclosed
US-20130153878-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-06-20 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 CYP1A1 216/4885CYP1A2 690/4885CYP1B1 979/4885
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 CYP1A1 216/4885CYP1A2 690/4885CYP1B1 979/4885
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 CYP1A1 194/4885CYP1A2 570/4885CYP1B1 932/4885
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 CYP1A1 216/4885CYP1A2 690/4885CYP1B1 979/4885
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 CYP1A1 216/4885CYP1A2 690/4885CYP1B1 979/4885
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 CYP1A1 216/4885CYP1A2 690/4885CYP1B1 979/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 CYP1A1 216/4885CYP1A2 690/4885CYP1B1 979/4885
US-20220223793-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, DRD1 CYP1A1 36/4885CYP1A2 122/4885CYP1B1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.