Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886126 | 0.90 | KCNH2 (0.62) | KCNH2SCN3AKDM4EALDH1A1GAA | |
| SCHEMBL5886076 | 0.90 | KCNH2 (0.62) | KCNH2SCN3AKDM4EALDH1A1GAA | |
| SCHEMBL5886212 | 0.90 | KCNH2 (0.62) | KCNH2SCN3AKDM4EALDH1A1GAA | |
| SCHEMBL31289649 | 0.85 | DPP4 (0.47) | KCNH2SCN3AGAA | |
| SCHEMBL31289648 | 0.85 | DPP4 (0.47) | KCNH2SCN3AGAA | |
| SCHEMBL8870852 | 0.85 | DPP4 (0.47) | KCNH2SCN3AGAA | |
| SCHEMBL4333611 | 0.84 | KCNH2 (0.40) | KCNH2SCN3AGAAS1PR4S1PR1 | |
| SCHEMBL8442870 | 0.84 | KCNH2 (0.41) | KCNH2SCN3AKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL8871065 | 0.83 | DPP4 (0.46) | KCNH2SCN3A | |
| Hydrochloric Acid SCHEMBL31289646 | 0.83 | DPP4 (0.46) | KCNH2SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203697-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2019094-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203697-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | CLIC4, NR3C2, MAN2B1 | KCNH2 1249/4885SCN3A 890/4885KDM4E 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.