Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.52 |
| ▸ | CNR2 | P34972 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318122 | 1.00 | CNR1 (0.52) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL3176889 | 1.00 | CNR1 (0.52) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL5792357 | 0.96 | CNR1 (0.55) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL31318123 | 0.96 | CNR1 (0.55) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL3011354 | 0.96 | CNR1 (0.55) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL7024508 | 0.78 | CNR1 (0.42) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL4089485 | 0.78 | SSTR4 (0.35) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL5792354 | 0.75 | ALDH1A1 (0.38) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL17237462 | 0.75 | ALDH1A1 (0.38) | CNR1CNR2ALDH1A1MAPTNPC1 | |
| SCHEMBL9700462 | 0.70 | CNR1 (0.66) | CNR1CNR2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303528-A1 | CB2 Receptor Modulators in Neurodegenerative Diseases and Applications of the Same | UNIV ARKANSAS (US) | 2013-11-14 | — | — | US | disclosed |
| US-20090124608-A1 | CB2 Receptor Modulators In Neurodegenerative Diseases And Applications Of The Same | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2009-05-14 | — | — | US | disclosed |