Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4090192 | 0.90 | HDAC1 (0.40) | HDAC1HDAC6DYRK3CISD1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL4090201 | 0.90 | HDAC1 (0.40) | HDAC1HDAC6DYRK3CISD1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL4089208 | 0.89 | HDAC1 (0.39) | HDAC1HDAC6DYRK3CISD1PIK3CD | |
| Trifluoroacetic Acid SCHEMBL4089216 | 0.89 | HDAC1 (0.39) | HDAC1HDAC6DYRK3CISD1PIK3CD | |
| SCHEMBL2983859 | 0.88 | HDAC1 (0.43) | HDAC1HDAC6DYRK3CISD1HDAC3 | |
| SCHEMBL2983860 | 0.88 | HDAC1 (0.43) | HDAC1HDAC6DYRK3CISD1HDAC3 | |
| SCHEMBL2993800 | 0.88 | HDAC1 (0.42) | HDAC1HDAC6DYRK3CISD1PIK3CD | |
| SCHEMBL2993804 | 0.88 | HDAC1 (0.42) | HDAC1HDAC6DYRK3CISD1PIK3CD | |
| SCHEMBL4091158 | 0.87 | DYRK3 (0.37) | HDAC1HDAC6DYRK3CISD1PIK3CD | |
| SCHEMBL2990906 | 0.87 | HDAC1 (0.44) | HDAC1HDAC6DYRK3CISD1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | HIPK3, HIPK1, HIPK4 | HDAC1 1549/4885HDAC6 194/4885DYRK3 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.