SCHEMBL4090313

SCHEMBL4090313

C[Si](C)(C)c1ccc(Nc2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.42
HPGD P15428 8/20 0.42
KDM4E B2RXH2 7/20 0.42
RAB9A P51151 5/20 0.42
MAPT P10636 5/20 0.42
NPC1 O15118 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
CASP3 P42574 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KMT2A Q03164 8/20 0.40
HSD17B10 Q99714 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 3/20 0.40
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
MEN1 O00255 6/20 0.40
GAA P10253 3/20 0.40
GLA P06280 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24425485 0.87 ALDH1A1 (0.40) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL15699019 0.85 KDM4E (0.53) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL2521923 0.84 KDM4E (0.57) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL29684910 0.82 AKR1C3 (0.49) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL25546783 0.82 KDM4E (0.42) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL24786179 0.82 KMT2A (0.51) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL14295749 0.82 AKR1C3 (0.49) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL23239603 0.82 AKR1C3 (0.49) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL16185374 0.82 MEN1 (0.47) ALDH1A1HPGDKDM4ERAB9AMAPT
SCHEMBL21086662 0.81 ALDH1A1 (0.42) ALDH1A1HPGDKDM4ERAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-01-27 US disclosed
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2021-06-01 US disclosed
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-08-13 US disclosed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US disclosed
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 US disclosed
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 US disclosed
US-9966535-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-08 US disclosed
US-9966535-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-08 US disclosed
US-20170317284-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-11-02 US disclosed
US-20170317284-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-11-02 US disclosed
US-20150171337-A1 AMINE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed
US-20150171337-A1 AMINE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed
US-20140312340-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140312340-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 US disclosed
US-20130153878-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-06-20 US disclosed
US-20130153878-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-06-20 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALDH1A1 470/4885HPGD 4245/4885KDM4E 586/4885
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALDH1A1 470/4885HPGD 4245/4885KDM4E 586/4885
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 ALDH1A1 306/4885HPGD 4140/4885KDM4E 404/4885
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALDH1A1 470/4885HPGD 4245/4885KDM4E 586/4885
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALDH1A1 470/4885HPGD 4245/4885KDM4E 586/4885
US-20170317284-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALDH1A1 470/4885HPGD 4245/4885KDM4E 586/4885
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALDH1A1 470/4885HPGD 4245/4885KDM4E 586/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALDH1A1 470/4885HPGD 4245/4885KDM4E 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.