SCHEMBL4091546

SCHEMBL4091546

CCOC(=O)/C=C/CC(=O)OCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.54
MAPT P10636 2/20 0.53
ALDH1A1 P00352 3/20 0.47
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
TTR P02766 1/20 0.46
DPP4 P27487 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CYP3A4 P08684 1/20 0.44
TRPA1 O75762 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
ATM Q13315 1/20 0.39
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61548 1.00 HCAR2 (0.54) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL13990116 1.00 HCAR2 (0.54) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL27761598 0.88 GAA (0.48) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL13405605 0.88 MAPT (0.50) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL6708068 0.84 GAA (0.57) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL6647774 0.84 GAA (0.57) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL12861650 0.83 MAPT (0.46) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL8093037 0.83 GAA (0.39) HCAR2MAPTALDH1A1MGAMGAA
SCHEMBL8925907 0.83 HCAR2 (0.54) HCAR2MAPTALDH1A1TTRDPP4
SCHEMBL10689168 0.83 GAA (0.46) HCAR2MAPTALDH1A1MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP disclosed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP disclosed
EP-4584243-B1 CROSSLINKERS HEMOTEQ AG (DE) 2025-11-05 EP disclosed
EP-4584245-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584244-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584243-A1 CROSSLINKERS Hemoteq AG (DE) 2025-07-16 EP disclosed
WO-2025056815-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES HEMOTEQ AG (DE) 2025-03-20 WO disclosed
WO-2025056813-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES HEMOTEQ AG (DE) 2025-03-20 WO disclosed
WO-2025056814-A1 CROSSLINKERS HEMOTEQ AG (DE) 2025-03-20 WO disclosed
EP-4524128-A1 BENZOPHENONE CROSSLINKERS Hemoteq AG (DE) 2025-03-19 EP disclosed
EP-1087963-A1 INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 Chiron Corporation (US) 2001-04-04 EP disclosed
WO-1999065897-A1 INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 CHIRON CORPORATION (US) 1999-12-23 WO disclosed
EP-0459561-B1 Dioxo-tetrahydroquinoline derivatives MERCK SHARP & DOHME (GB) 1995-09-20 EP disclosed
US-5268378-A Oxo group in 2 and 4 position MERCK SHARP & DOHME, LIMITED (GB) 1993-12-07 US disclosed
US-5231102-A Tetrahydroquinoline derivatives useful for neurodegenerative disorders MERCK SHARP & DOHME, LTD. (GB) 1993-07-27 US disclosed
EP-0459561-A2 Dioxo-tetrahydroquinoline derivatives MERCK SHARP & DOHME LTD. (GB) 1991-12-04 EP disclosed
US-5026845-A 1,4-diazabicyclo[3.2.2.]nonane and intermediates for the preparation thereof FRIEDMANN ROBERT C (US) 1991-06-25 US disclosed
EP-0386839-A2 Tetrahydroquinoline derivatives useful for neurodegenerative disorders MERCK SHARP & DOHME LTD. (GB) 1990-09-12 EP disclosed
US-4895943-A Preparation of 1,4-diazabicyclo(3.2.2)nonane PFIZER INC. (US) 1990-01-23 US disclosed
US-4113705-A Triisocyanates useful for the production of polyurethane resins BAYER AKTIENGESELLSCHAFT (DE) 1978-09-12 US disclosed