SCHEMBL8925907

SCHEMBL8925907

CCOC(=O)C=CCC(C)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.54
MAPT P10636 5/20 0.53
ALDH1A1 P00352 4/20 0.51
LMNA P02545 3/20 0.42
HSD17B10 Q99714 1/20 0.42
TTR P02766 1/20 0.42
DPP4 P27487 1/20 0.42
NPSR1 Q6W5P4 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CYP3A4 P08684 1/20 0.40
ATM Q13315 1/20 0.39
RAB9A P51151 1/20 0.38
GLO1 Q04760 1/20 0.38
MDM2 Q00987 1/20 0.37
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61548 0.83 HCAR2 (0.54) HCAR2MAPTALDH1A1TTRDPP4
SCHEMBL13990116 0.83 HCAR2 (0.54) HCAR2MAPTALDH1A1TTRDPP4
SCHEMBL4091546 0.83 HCAR2 (0.54) HCAR2MAPTALDH1A1TTRDPP4
SCHEMBL8022129 0.83 HCAR2 (0.59) HCAR2MAPTALDH1A1LMNATTR
Diethyl Maleate SCHEMBL28692587 0.81 HCAR2 (0.76) HCAR2MAPTALDH1A1LMNAHSD17B10
SCHEMBL10884940 0.80 ATM (0.68) HCAR2MAPTALDH1A1NPSR1ATM
SCHEMBL94678 0.79
SCHEMBL691584 0.79
Diethyl Maleate SCHEMBL28618621 0.79 HCAR2 (0.67) HCAR2MAPTALDH1A1LMNAHSD17B10
SCHEMBL264771 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
US-5156718-A Made from kraft wood pulp, adjuvants and a binder of a conjugated diene, aromatic vinyl, acrylic and an activatable (hydrolizable) acrylic ester monomer; floor tiles; tensile strength GENCORP INC. (US) 1992-10-20 US claimed
EP-0470689-A1 Copolymer binders GENCORP INC. (US) 1992-02-12 EP claimed
EP-0426280-A1 Paper mats GENCORP INC. (US) 1991-05-08 EP claimed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US claimed
US-5629047-A IMPROVED TENSILE STRENGTH, LOW TEMPERATURE POLYMERIZATION GENCORP INC. (US) 1997-05-13 US disclosed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US disclosed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP disclosed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US disclosed
US-5156718-A Made from kraft wood pulp, adjuvants and a binder of a conjugated diene, aromatic vinyl, acrylic and an activatable (hydrolizable) acrylic ester monomer; floor tiles; tensile strength GENCORP INC. (US) 1992-10-20 US disclosed
EP-0470689-A1 Copolymer binders GENCORP INC. (US) 1992-02-12 EP disclosed
EP-0426280-A1 Paper mats GENCORP INC. (US) 1991-05-08 EP disclosed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US disclosed
US-4778869-A COATINGS, ADHESIVES, MOLDINGS AMERICAN CYANAMID COMPANY (US) 1988-10-18 US disclosed
US-4656308-A COATINGS AMERICAN CYANAMID COMPANY (US) 1987-04-07 US disclosed
EP-0020000-B1 ACTIVATED ESTER MONOMERS, POLYMERS FORMED THEREFROM AND COATING COMPOSITIONS CONTAINING SAID POLYMERS AMERICAN CYANAMID COMPANY (US) 1983-06-15 EP disclosed
EP-0049910-A2 Copolymers formed from activated ester monomers, and coating compositions containing said copolymers AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP disclosed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP disclosed