SCHEMBL4091574

SCHEMBL4091574

CCOC(=O)c1cc(Nc2ccc(C)cc2)c(C(=O)O)cc1Nc1ccc(C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 6/20 0.57
AKR1C2 P52895 6/20 0.57
ATM Q13315 1/20 0.50
ALOX5 P09917 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
GFER P55789 2/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
NPSR1 Q6W5P4 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
DHODH Q02127 2/20 0.44
CASP3 P42574 1/20 0.44
NGLY1 Q96IV0 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8834179 0.91 AKR1C3 (0.53) AKR1C3AKR1C2ATMALOX5SMN1; SMN2
SCHEMBL8529855 0.90 ATM (0.58) AKR1C3AKR1C2ATMALOX5SMN1; SMN2
SCHEMBL4254887 0.87 AKR1C3 (0.65) AKR1C3AKR1C2SMN1; SMN2MAPTKDM4E
SCHEMBL936023 0.86 AKR1C3 (0.69) AKR1C3AKR1C2SMN1; SMN2MAPTKDM4E
SCHEMBL5846272 0.85 ATM (0.62) AKR1C3AKR1C2ATMSMN1; SMN2MAPT
SCHEMBL11647944 0.82 MAPT (0.65) AKR1C3AKR1C2SMN1; SMN2MAPTKDM4E
SCHEMBL8834022 0.81 EGFR (0.45) AKR1C3AKR1C2ATMSMN1; SMN2MAPT
SCHEMBL3237464 0.81 ATM (0.52) AKR1C3AKR1C2ATMALOX5SMN1; SMN2
SCHEMBL8834499 0.81 ATM (0.58) AKR1C3AKR1C2ATMMAPTGFER
SCHEMBL8834296 0.81 MAPT (0.50) AKR1C3AKR1C2ATMSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149439-A1 CONDUCTIVE ADHESIVE COMPOSITION AND CONDUCTIVE ADHESIVE FILM USING SAME 주식회사 제이에이치씨 2020-07-23 WO disclosed
US-20090017307-A1 Process for the Preparation of Organic Materials MCA TECHNOLOGIES, GMBH (CH) 2009-01-15 US disclosed
US-20080060554-A1 Process for the Preparation of Organic Materials MCA TECHNOLOGIES, GMBH (CH) 2008-03-13 US disclosed
US-20070119345-A1 Process for the preparation of organic materials MCA TECHNOLOGIES, GMBH (CH) 2007-05-31 US disclosed
EP-1725619-A1 PROCESS FOR THE PREPARATION OF ORGANIC PIGMENTS MCA Technologies GMBH (CH) 2006-11-29 EP disclosed
WO-2005085364-A1 PROCESS FOR THE PREPARATION OF ORGANIC PIGMENTS MCA TECHNOLOGIES GMBH (CH) 2005-09-15 WO disclosed
US-5347038-A Starting material for quinacridone pigments, pollution control, from succinic acid diester and aniline HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090017307-A1 Process for the Preparation of Organic Materials KLK4, PDK4, GRK1 AKR1C3 196/4885AKR1C2 321/4885ATM 1603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.