Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 14/20 | 0.65 |
| ▸ | AKR1C2 | P52895 | 14/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091568 | 0.94 | AKR1C3 (0.59) | AKR1C3AKR1C2MAPTALOX15LMNA | |
| SCHEMBL9409087 | 0.91 | AKR1C3 (0.61) | AKR1C3AKR1C2MAPTALOX15LMNA | |
| SCHEMBL936023 | 0.90 | AKR1C3 (0.69) | AKR1C3AKR1C2MAPTLMNAKMT2A | |
| SCHEMBL4257100 | 0.87 | MAPT (0.68) | AKR1C3AKR1C2MAPTALOX15LMNA | |
| SCHEMBL8834176 | 0.87 | AKR1C3 (0.55) | AKR1C3AKR1C2MAPTALOX15LMNA | |
| SCHEMBL4091574 | 0.87 | AKR1C3 (0.57) | AKR1C3AKR1C2MAPTLMNAKMT2A | |
| SCHEMBL8773601 | 0.86 | AKR1C3 (0.81) | AKR1C3AKR1C2MAPTLMNAKMT2A | |
| SCHEMBL14598926 | 0.86 | AKR1C3 (0.81) | AKR1C3AKR1C2MAPTLMNAKMT2A | |
| SCHEMBL8773607 | 0.86 | AKR1C3 (0.71) | AKR1C3AKR1C2MAPTLMNAKMT2A | |
| SCHEMBL11647944 | 0.85 | MAPT (0.65) | AKR1C3AKR1C2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263771-B2 | Method for manufacturing dispersion of quinoline derivative | CANON KABUSHIKI KAISHA (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20090020043-A1 | METHOD FOR MANUFACTURING DISPERSION OF QUINOLINE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2009-01-22 | — | — | US | disclosed |