Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836056 | 0.82 | MET (0.43) | MET | |
| SCHEMBL837714 | 0.80 | MET (0.54) | METCDKL5 | |
| SCHEMBL838098 | 0.79 | MET (0.49) | MET | |
| SCHEMBL14291366 | 0.78 | MET (0.41) | MET | |
| SCHEMBL835600 | 0.77 | MET (0.59) | METCDKL5 | |
| SCHEMBL837534 | 0.77 | MET (0.56) | METCDKL5 | |
| SCHEMBL836523 | 0.77 | MET (0.51) | MET | |
| SCHEMBL837508 | 0.76 | MET (0.54) | METCDKL5 | |
| SCHEMBL836073 | 0.76 | MET (0.49) | MET | |
| SCHEMBL836134 | 0.76 | MET (0.56) | METCDKL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057164-A1 | TRIAZOLOTRIAZINES AS KINASE INHIBITORS | Incyte Corporation (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008021781-A1 | TRIAZOLOTRIAZINES AS KINASE INHIBITORS | INCYTE CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |