Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | GCGR | P47871 | 7/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 3/20 | 0.47 |
| ▸ | ADCY3 | O60266 | 3/20 | 0.47 |
| ▸ | ADCY9 | O60503 | 3/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.47 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.47 |
| ▸ | ADCY7 | P51828 | 3/20 | 0.47 |
| ▸ | ADCY2 | Q08462 | 3/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.47 |
| ▸ | ADCY4 | Q8NFM4 | 3/20 | 0.47 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | GCG | P01275 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091187 | 0.91 | GCGR (0.53) | MCHR1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL4091754 | 0.90 | MCHR1 (0.47) | MCHR1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL4081585 | 0.88 | GCGR (0.57) | MCHR1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL4087094 | 0.86 | MCHR1 (0.48) | MCHR1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL2650947 | 0.82 | F2 (0.44) | MCHR1GCGRF2F7GCG | |
| SCHEMBL4087196 | 0.82 | GCGR (0.58) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4087190 | 0.82 | GCGR (0.58) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4081393 | 0.82 | GCGR (0.64) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4086773 | 0.82 | GCGR (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4087498 | 0.81 | GCGR (0.66) | MCHR1GCGRADCY6ADCY3ADCY9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| US-6875760-B2 | Glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2005-04-05 | — | — | US | disclosed |
| US-20030220350-A1 | Glucagon antagonists/inverse agonists | PFIZER INC | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | GLP1R, GPR119, GCGR | MCHR1 178/4885GCGR 3/4885ADCY6 956/4885 |
| US-20030220350-A1 | Glucagon antagonists/inverse agonists | GLP1R, GPR119, GCGR | MCHR1 178/4885GCGR 3/4885ADCY6 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.