SCHEMBL4091846

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15101689	0.89	HSP90AA1 (0.55)	HSP90AA1HSP90AB1AGPAT2KDM4EALDH1A1
	SCHEMBL4086652	0.85	HSP90AA1 (0.50)	HSP90AA1HSP90AB1PIM1DHFREGFR
	SCHEMBL4098532	0.84	HSP90AA1 (0.46)	HSP90AA1HSP90AB1PIM1DHFREGFR
	SCHEMBL13927550	0.83	HSP90AA1 (0.48)	HSP90AA1HSP90AB1PIM1DHFREGFR
	SCHEMBL4085848	0.83	EGFR (0.45)	HSP90AA1HSP90AB1DHFREGFRTYMS
	SCHEMBL13927519	0.83	HSP90AA1 (0.48)	HSP90AA1HSP90AB1DHFREGFRTYMS
	SCHEMBL4093485	0.81	DHFR (0.46)	HSP90AA1HSP90AB1DHFREGFRTYMS
	SCHEMBL4096143	0.80	NPC1 (0.47)	HSP90AA1HSP90AB1AGPAT2ALDH1A1DHFR
	SCHEMBL4093475	0.80	NPC1 (0.43)	HSP90AA1HSP90AB1DHFREGFRTYMS
	SCHEMBL4102784	0.80	HSP90AB1 (0.45)	HSP90AA1HSP90AB1PIM1DHFREGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.