SCHEMBL4092435

SCHEMBL4092435

CCCCCCCCC=CCCCCCCCCCS(=O)(=O)O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.75
FAAH O00519 5/20 0.56
PPARA Q07869 4/20 0.55
TRPV1 Q8NER1 1/20 0.54
TERT O14746 3/20 0.52
CYP1A2 P05177 2/20 0.52
MAPT P10636 2/20 0.52
CYP2C19 P33261 2/20 0.52
BLM P54132 2/20 0.52
HSD17B10 Q99714 2/20 0.52
FABP4 P15090 2/20 0.52
PTPN1 P18031 2/20 0.52
PPARG P37231 2/20 0.52
KMT2A Q03164 2/20 0.52
PPARD Q03181 2/20 0.52
GMNN O75496 1/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
POLB P06746 1/20 0.52
CYP2C9 P11712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11003091 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL1962433 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL9777847 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL8349583 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL11370740 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL11370737 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL4092428 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL2219389 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL1962429 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT
SCHEMBL9777844 1.00 EPHX2 (0.75) EPHX2FAAHPPARATRPV1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3231790-B1 METHOD FOR PRODUCING CATIONIC LIPID NOF CORP (JP) 2019-11-06 EP disclosed
CN-107001238-B The manufacturing method of cation lipid 日油株式会社 2019-04-26 CN disclosed
US-9834502-B2 Method for producing cationic lipid NOF CORPORATION (JP) 2017-12-05 US disclosed
EP-3231790-A1 METHOD FOR PRODUCING CATIONIC LIPID NOF Corporation (JP) 2017-10-18 EP disclosed
US-20170275242-A1 METHOD FOR PRODUCING CATIONIC LIPID NOF CORPORATION (JP) 2017-09-28 US disclosed
CN-107001238-A The manufacture method of cation lipid 日油株式会社 2017-08-01 CN disclosed
WO-2009118712-A2 NOVEL DIHYDROXYPYRROLIDINE DERIVATIVES AS ANTI-CANCER AGENTS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2009-10-01 WO disclosed
WO-1999033851-A1 N-HET-SUBSTITUTED GLYCEROPHOSPHOETHANOLAMINES CLARION PHARMACEUTICALS, INC. (US) 1999-07-08 WO disclosed
EP-0523189-B1 CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES VICAL INC (US) 1999-06-16 EP disclosed
US-5730157-A GLYCEROPHOSPHOETHANOLAMINES CLARION PHARMACEUTICALS INC. (US) 1998-03-24 US disclosed
US-5703062-A ANTITUMOR AGENT; SKIN DISORDERS; ANTIINFLAMMATORY AGENTS CLARION PHARMACEUTICALS INC. (US) 1997-12-30 US disclosed
US-5665714-A N-substituted glycerophosphoethanolamines CLARION PHARMACEUTICALS INC. (US) 1997-09-09 US disclosed
US-5459127-A Drug delivery, extracellular treatment VICAL, INC. (US) 1995-10-17 US disclosed
EP-0523189-A4 VICAL INC (US) 1995-04-26 EP disclosed
US-5264618-A For transport of biological active agents into cells for viral agents or polynucleotides or immunogenic peptides VICAL, INC. (US) 1993-11-23 US disclosed
EP-0523189-A1 CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES VICAL, INC. (US) 1993-01-20 EP disclosed
WO-1991016024-A1 CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES VICAL, INC. (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170275242-A1 METHOD FOR PRODUCING CATIONIC LIPID LIPA, LIPC, CETP EPHX2 1986/4885FAAH 703/4885PPARA 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.