Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256089 | 0.82 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL12639929 | 0.82 | KMT2A (0.61) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL29851669 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL880655 | 0.79 | KMT2A (0.53) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL616596 | 0.79 | KMT2A (0.56) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL853922 | 0.78 | KMT2A (0.51) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL4318877 | 0.77 | MAPT (0.68) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL14314281 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AGAAALDH1A1CHRM1 | |
| SCHEMBL10274875 | 0.77 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL748985 | 0.77 | GAA (0.58) | SMN1; SMN2GAAALDH1A1CHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186874-A1 | Carboxamide derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186874-A1 | Carboxamide derivative and use thereof | NTSR2, NTSR1, CNR2 | SMN1; SMN2 631/4885MEN1 492/4885KMT2A 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.