Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.39 |
| ▸ | BCL2 | P10415 | 4/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097942 | 0.88 | PTGES (0.57) | PTGESMCL1BCL2MDM2MCHR1 | |
| SCHEMBL3571518 | 0.83 | PTGES (0.68) | PTGESPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL4096225 | 0.80 | PTGES (0.54) | PTGESMCL1BCL2MDM2MCHR1 | |
| SCHEMBL4101699 | 0.79 | PTGES (0.48) | PTGESMCL1BCL2MDM2PTGDR | |
| SCHEMBL4101700 | 0.79 | PTGES (0.48) | PTGESMCL1BCL2MDM2PTGDR | |
| SCHEMBL3627558 | 0.79 | PTGES (0.68) | PTGESPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL4086721 | 0.78 | PTGES (0.48) | PTGESMCL1BCL2MDM2ACACB | |
| SCHEMBL4105667 | 0.78 | PTGES (0.48) | PTGESMCL1BCL2MDM2MCHR1 | |
| SCHEMBL4091286 | 0.77 | PTGES (0.44) | PTGESMCL1BCL2MDM2MCHR1 | |
| SCHEMBL4098949 | 0.77 | PTGES (0.41) | PTGESMCL1BCL2MDM2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | PTGES 3/4885PIK3CD 4576/4885PIK3CA 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.