⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015688 | 0.86 | ALDH1A1 (0.33) | — | |
| SCHEMBL1272671 | 0.83 | — | — | |
| SCHEMBL19578556 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL2893660 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL4100814 | 0.77 | — | — | |
| SCHEMBL20799751 | 0.77 | MEN1 (0.32) | — | |
| SCHEMBL19091318 | 0.75 | — | — | |
| SCHEMBL15787142 | 0.73 | CYP2C19 (0.50) | — | |
| SCHEMBL27383911 | 0.73 | CYP2C19 (0.48) | — | |
| SCHEMBL7852755 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | claimed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | claimed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | claimed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | claimed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | claimed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | claimed |
| EP-4393959-A1 | HUMAN TRANSFERRIN RECEPTOR-BINDING ANTIBODY-PEPTIDE CONJUGATE | PeptiDream Inc. (JP) | 2024-07-03 | — | — | EP | disclosed |
| US-20230285338-A9 | METHODS FOR TREATING MICROGLIAL DYSFUNCTION | WASHINGTON UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| WO-2023001607-A1 | MICRONEEDLE ARRAY WITH ANTISEPTICS | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2023-01-26 | — | — | WO | disclosed |
| US-11318137-B2 | Quinazoline compounds as modulators of Ras signaling | VANDERBILT UNIVERSITY (US) | 2022-05-03 | — | — | US | disclosed |
| WO-2021221656-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | SYNEDGEN, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
| US-20210290561-A1 | PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-09-23 | — | — | US | disclosed |
| US-20210186906-A1 | METHODS, COMPOSITIONS, AND KITS FOR TREATING PAIN AND PRURITIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-24 | — | — | US | disclosed |
| EP-0051787-B1 | AMIDINES AND AMIDINE/ISOCYANATE ADDUCTS, METHODS OF PREPARING THEM AND THEIR USE AS CATALYSTS IN CURING EPOXY RESINS | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4455425-A | EPOXY RESINS, CURING AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-19 | — | — | US | disclosed |
| US-4455426-A | CATALYST FOR HARDENING EPOXY RESINS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-19 | — | — | US | disclosed |
| US-4424313-A | ORGANO-NITROGEN SALTS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-03 | — | — | US | disclosed |
| US-4424353-A | INTERMEDIATES FOR ISOCYANATE ADDUCTS, EPOXY RESIN CURING AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-03 | — | — | US | disclosed |
| EP-0085913-A1 | Reactive polymers containing carboxylic groups, process for their production and their use as curing agents in powder lacquers | BAYER AG (DE) | 1983-08-17 | — | — | EP | disclosed |
| EP-0051787-A2 | Amidines and amidine/isocyanate adducts, methods of preparing them and their use as catalysts in curing epoxy resins | BAYER AG (DE) | 1982-05-19 | — | — | EP | disclosed |