Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470694 | 0.90 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL4095160 | 0.89 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL463047 | 0.88 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL463046 | 0.88 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL3828552 | 0.88 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL463045 | 0.88 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL4095711 | 0.85 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL15051793 | 0.85 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL461628 | 0.84 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL15051434 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059504-A1 | 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS | Rottapharm S.p.A. (IT) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008014821-A1 | 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS | ROTTAPHARM S.P.A. (IT) | 2008-02-07 | — | — | WO | disclosed |