Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 20/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 19/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096955 | 0.93 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL4099927 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2719382 | 0.91 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2717867 | 0.84 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2721364 | 0.83 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2717381 | 0.82 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2717253 | 0.82 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2721475 | 0.82 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2719378 | 0.80 | PIK3CD (0.74) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL2720010 | 0.80 | PIK3CD (0.74) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061696-A1 | 5 -CYANO-4, 6 -DIAMINOPYRIMIDINE OR 6 -AMINOPURINE DERIVATIVES AS PI3K- DELTA INHIBITORS | AMGEN INC. (US) | 2012-05-10 | — | — | WO | disclosed |