Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 13/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 13/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623645 | 0.90 | MAPT (0.40) | L3MBTL1AKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL4613753 | 0.88 | HSD17B10 (0.59) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL4623376 | 0.86 | AKR1C3 (0.57) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL15507330 | 0.86 | KDM4E (0.60) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL8306753 | 0.86 | CDC25B (0.52) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL19329021 | 0.84 | KDM4E (0.58) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL11951528 | 0.84 | POLB (0.63) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL11704191 | 0.82 | HSD17B10 (0.52) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL11951520 | 0.81 | POLB (0.65) | CDC25ACDC25BHSD17B10TDP1POLB | |
| SCHEMBL12300194 | 0.81 | CDC25A (0.47) | CDC25ACDC25BHSD17B10TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | CDC25A 396/4885CDC25B 660/4885HSD17B10 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.