Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093150 | 0.90 | CDC25A (0.47) | AKR1C3AKR1C2ALDH1A1L3MBTL1AKR1B10 | |
| SCHEMBL21985528 | 0.85 | SMN1; SMN2 (0.39) | MAPTRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL50489 | 0.84 | AKR1C3 (0.49) | MAPTRAB9ASMN1; SMN2NPC1AKR1C3 | |
| SCHEMBL29361599 | 0.84 | AKR1C3 (0.49) | MAPTRAB9ASMN1; SMN2NPC1AKR1C3 | |
| SCHEMBL10046615 | 0.82 | L3MBTL1 (0.48) | MAPTSMN1; SMN2AKR1C3AKR1C2HPGD | |
| SCHEMBL7898447 | 0.80 | KDM4E (0.52) | MAPTRAB9ASMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL29440655 | 0.79 | ALDH1A1 (0.40) | MAPTSMN1; SMN2HPGDALDH1A1TSHR | |
| SCHEMBL75886 | 0.79 | ALDH1A1 (0.40) | MAPTSMN1; SMN2HPGDALDH1A1TSHR | |
| SCHEMBL10802946 | 0.78 | PARP1 (0.45) | SMN1; SMN2ALDH1A1MAPK1TSHRKMT2A | |
| SCHEMBL28767016 | 0.78 | ALDH1A1 (0.44) | MAPTRAB9ASMN1; SMN2NPC1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102727493-B | Applications of TEMPOL derivatives as anti-tumor drugs | FOURTH MILITARY MEDICAL UNIV | 2014-04-23 | — | — | CN | disclosed |
| CN-102727493-A | Applications of TEMPOL derivatives as anti-tumor drugs | FOURTH MILITARY MEDICAL UNIV | 2012-10-17 | — | — | CN | disclosed |
| EP-0886639-B1 | SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES | GLYCOMIMETICS INC (US) | 2008-05-28 | — | — | EP | disclosed |
| US-6187754-B1 | Sialyl-Lewisa and sialyl-Lewisx epitode analogues | GLYCOTECH CORP. | 2001-02-13 | — | — | US | disclosed |
| EP-0886639-A1 | SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES | GlycoTech Corp. (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997028174-A1 | SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES | NOVARTIS AG (CH) | 1997-08-07 | — | — | WO | disclosed |