Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4093271 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTPKMLMNAKDM4E | |
| SCHEMBL1253519 | 0.93 | ALDH1A1 (0.45) | ALDH1A1MAPTPKMLMNAKDM4E | |
| SCHEMBL1253522 | 0.93 | ALDH1A1 (0.45) | ALDH1A1MAPTPKMLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1254717 | 0.92 | ALDH1A1 (0.44) | ALDH1A1MAPTPKMLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1253441 | 0.92 | ALDH1A1 (0.44) | ALDH1A1MAPTPKMLMNAKDM4E | |
| SCHEMBL4093269 | 0.83 | MAPT (0.39) | ALDH1A1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL21963765 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL30161257 | 0.77 | — | — | |
| SCHEMBL3888550 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTPKMLMNAKDM4E | |
| SCHEMBL3888548 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTPKMLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | DEBIOPHARM INTERNATIONAL SA (CH) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | GAA, TFPI, DBI | ALDH1A1 2669/4885MAPT 4213/4885PKM 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.