Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RPA1 | P27694 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | RECQL | P46063 | 4/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816556 | 0.89 | RPA1 (0.64) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL13902114 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL13901814 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL13389277 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL13902075 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL892788 | 0.79 | HTR2A (0.50) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL13902097 | 0.78 | STAT3 (0.52) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL1984665 | 0.76 | RPA1 (0.68) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL13902117 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL13902082 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | KDM4E 4055/4885ALDH1A1 1426/4885MAPT 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.