Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755498 | 0.87 | PDE5A (0.42) | PDE5ANPSR1NPC1LMNATP53 | |
| SCHEMBL9846238 | 0.85 | PDE5A (0.41) | PDE5ANPSR1LMNATP53MAPT | |
| SCHEMBL9502127 | 0.84 | PDE5A (0.42) | PDE5ANPSR1LMNATP53MAPT | |
| SCHEMBL9500848 | 0.82 | KMT2A (0.43) | PDE5ANPSR1NPC1LMNATP53 | |
| SCHEMBL4093897 | 0.81 | PDE5A (0.46) | PDE5ANPSR1BLMKDM4ENPC1 | |
| SCHEMBL9768521 | 0.79 | PDE5A (0.52) | PDE5ANPSR1LMNATP53MAPT | |
| SCHEMBL10479352 | 0.79 | CHRM2 (0.47) | PDE5ANPSR1LMNATP53MAPT | |
| SCHEMBL9437957 | 0.79 | CHRM2 (0.47) | PDE5ANPSR1LMNATP53MAPT | |
| SCHEMBL23406316 | 0.78 | SRC (0.43) | PDE5ANPSR1LMNATP53MAPT | |
| SCHEMBL3656115 | 0.78 | SRC (0.43) | PDE5ANPSR1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009059872-A1 | FRAGRANCING COMPOSITION COMPRISING A COMBINATION OF A BENZOTRIAZOLE COMPOUND, A UVA SCREENING AGENT OF THE DIBENZOYLMETHANE TYPE AND A PARTICULAR UVB SCREENING SYSTEM | L'OREAL (FR) | 2009-05-14 | — | — | WO | claimed |