Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437957 | 0.72 | CHRM2 (0.47) | PDE5AHPGDTP53MAPTLMNA | |
| SCHEMBL8665350 | 0.72 | F7 (0.53) | MAPTKDM4EALOX15HSD17B10F7 | |
| SCHEMBL8665344 | 0.72 | F7 (0.53) | MAPTKDM4EALOX15HSD17B10F7 | |
| Linoleic Acid SCHEMBL28080406 | 0.71 | PPARG (0.59) | CYP3A4HPGDTP53CYP1A2MAPT | |
| SCHEMBL23406316 | 0.71 | SRC (0.43) | PDE5ATP53MAPTLMNANPSR1 | |
| SCHEMBL10475045 | 0.71 | SRC (0.43) | PDE5ATP53MAPTLMNANPSR1 | |
| SCHEMBL3656115 | 0.71 | SRC (0.43) | PDE5ATP53MAPTLMNANPSR1 | |
| SCHEMBL27315241 | 0.71 | SRC (0.43) | PDE5ATP53MAPTLMNANPSR1 | |
| SCHEMBL7684623 | 0.71 | SRC (0.43) | PDE5ATP53MAPTLMNANPSR1 | |
| SCHEMBL5699358 | 0.71 | MAPT (0.45) | CYP3A4HPGDTP53CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009059872-A1 | FRAGRANCING COMPOSITION COMPRISING A COMBINATION OF A BENZOTRIAZOLE COMPOUND, A UVA SCREENING AGENT OF THE DIBENZOYLMETHANE TYPE AND A PARTICULAR UVB SCREENING SYSTEM | L'OREAL (FR) | 2009-05-14 | — | — | WO | claimed |