Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320401 | 0.86 | ABCB1 (0.56) | ABCB1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL717390 | 0.81 | ABCB1 (0.49) | ABCB1ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL2840420 | 0.80 | ABCB1 (0.55) | ABCB1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL4102929 | 0.80 | ABCB1 (0.55) | ABCB1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL721278 | 0.78 | ABCB1 (0.63) | ABCB1ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL4092984 | 0.77 | KDM4E (0.41) | CA2ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL13799991 | 0.77 | KDM4E (0.41) | CA2ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL21358498 | 0.77 | KDM4E (0.41) | CA2ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL8183283 | 0.76 | CA2 (0.54) | ABCB1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL14493816 | 0.73 | ABCB1 (0.48) | ABCB1CA2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | DEBIOPHARM INTERNATIONAL SA (CH) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156578-A1 | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents | GAA, TFPI, DBI | ABCB1 972/4885CA2 2091/4885ALDH1A1 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.