Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681188 | 0.91 | POLB (0.55) | SMN1; SMN2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL718675 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL5025713 | 0.84 | POLB (0.55) | SMN1; SMN2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL4685138 | 0.83 | FAAH (0.54) | SMN1; SMN2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL4682094 | 0.81 | SMN1; SMN2 (0.79) | SMN1; SMN2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL4682039 | 0.78 | MAPT (0.76) | SMN1; SMN2POLBTDP1MAPTL3MBTL1 | |
| SCHEMBL4089570 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL4100533 | 0.78 | TLR8 (0.49) | TLR8AGER | |
| SCHEMBL25229993 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL18003909 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2POLBTDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1854784-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | PPARG, PPARA, PPARD | SMN1; SMN2 4112/4885POLB 1081/4885TDP1 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.