Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL81278 | 0.88 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL7859280 | 0.87 | ALDH1A1 (0.71) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| Phthalic Acid SCHEMBL29248354 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| Phthalic Acid SCHEMBL28573360 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| Phthalic Acid SCHEMBL3775119 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| Phthalic Acid SCHEMBL28780791 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| Phthalic Acid SCHEMBL30004352 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL7867317 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL11591181 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL234832 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4EMEN1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993580-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | Moleac Pte Ltd. (SG) | 2008-11-26 | — | — | EP | claimed |
| WO-2007106049-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | MOLEAC PTE LTD (SG) | 2007-09-20 | — | — | WO | claimed |
| EP-2508191-A1 | Combination therapy for treatment of patients with neurological disorders and cerebral infarction | Moleac Pte Ltd. (SG) | 2012-10-10 | — | — | EP | disclosed |
| US-20090162459-A1 | Combination Therapy for Treatment of Patients with Neurological Disorders and Cerebral Infarction | MOLEAC PTE. LTD (SG) | 2009-06-25 | — | — | US | disclosed |
| EP-1993580-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | Moleac Pte Ltd. (SG) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007106049-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | MOLEAC PTE LTD (SG) | 2007-09-20 | — | — | WO | disclosed |