Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.78 |
| ▸ | CCR5 | P51681 | 6/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613433 | 1.00 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| SCHEMBL4337252 | 1.00 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| SCHEMBL4337246 | 1.00 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| Trifluoroacetic Acid SCHEMBL4147670 | 0.97 | CCR2 (0.74) | CCR2KCNH2CCR5 | |
| SCHEMBL6014817 | 0.90 | CCR2 (0.63) | CCR2KCNH2CCR5 | |
| SCHEMBL6014819 | 0.90 | CCR2 (0.63) | CCR2KCNH2CCR5 | |
| SCHEMBL13335005 | 0.90 | CCR2 (0.63) | CCR2KCNH2CCR5 | |
| SCHEMBL4340648 | 0.88 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| SCHEMBL13613431 | 0.88 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| SCHEMBL4340652 | 0.88 | CCR2 (0.78) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763347-A4 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2009-05-20 | — | — | EP | claimed |
| EP-1763347-A2 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | Incyte Corporation (US) | 2007-03-21 | — | — | EP | claimed |
| WO-2006004741-A2 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2006-01-12 | — | — | WO | claimed |