Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954906 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL17491249 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL208069 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL18855 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL21616894 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL11459320 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL17491360 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL5415838 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL284122 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA | |
| SCHEMBL18662878 | 0.95 | HMGCR (0.46) | HMGCRPPARGPTGESALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090202462-A1 | SOLID COSMETIC COMPOSTION COMPRISING A POLYESTER | L'OREAL (FR) | 2009-08-13 | — | — | US | disclosed |
| US-5316713-A | Rubber tube manufacture, with film laminate overwrap | DU PONT CANADA INC. (CA) | 1994-05-31 | — | — | US | disclosed |
| EP-0315407-B1 | HIGH TEMPERATURE RELEASE SHEET FOR PRINTED CIRCUIT BOARDS | Du Pont Canada Inc. (CA) | 1993-01-20 | — | — | EP | disclosed |
| US-5043041-A | Nylon film containing heat stabilizer and inorganic particulate antiblock additive | DU PONT CANADA INC. (CA) | 1991-08-27 | — | — | US | disclosed |
| US-4966960-A | NYLON, INORGANIC PARTICULATE ANTI-BLOCK ADDITIVE, HEAT STABILIZER | DU PONT CANADA INC. (CA) | 1990-10-30 | — | — | US | disclosed |
| EP-0315407-A2 | High temperature release sheet for printed circuit boards | Du Pont Canada Inc. (CA) | 1989-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202462-A1 | SOLID COSMETIC COMPOSTION COMPRISING A POLYESTER | CUTA, LARS1, SUCLG1 | HMGCR 471/4885PPARG 843/4885PTGES 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.