Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.75 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15289000 | 0.86 | MEN1 (1.00) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL29532454 | 0.86 | MEN1 (1.00) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL15814046 | 0.86 | SLC22A6 (1.00) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Vanillic Acid SCHEMBL8853970 | 0.85 | MEN1 (0.70) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Apocynin SCHEMBL464770 | 0.84 | MEN1 (0.75) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Vanillic Acid SCHEMBL26179 | 0.84 | HTT (1.00) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Apocynin SCHEMBL29364797 | 0.84 | MEN1 (0.75) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Apocynin SCHEMBL109514 | 0.84 | MEN1 (0.75) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Vanillic Acid SCHEMBL9711598 | 0.84 | HTT (1.00) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Vanillic Acid SCHEMBL29378740 | 0.84 | HTT (1.00) | MEN1KMT2ASLC22A6SLC22A8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023127699-A1 | MODIFIED VINYL ALCOHOL POLYMER AND METHOD FOR PRODUCING SAME | 株式会社クラレ | 2023-07-06 | — | — | WO | disclosed |
| EP-1773779-B1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIV LAVAL (CA) | 2013-12-04 | — | — | EP | disclosed |
| US-8557804-B2 | Nicotinic receptor agonists for the treatment of inflammatory diseases | UNIVERSITE LAVAL (CA) | 2013-10-15 | — | — | US | disclosed |
| US-8551983-B2 | Nicotinic receptor agonists for the treatment of inflammatory diseases | UNIVERSITE LAVAL (CA) | 2013-10-08 | — | — | US | disclosed |
| US-20120022049-A1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSITE LAVAL (CA) | 2012-01-26 | — | — | US | disclosed |
| US-8039459-B2 | especially dimethylphenylpiperazinium; treating a variety of pulmonary diseases with fewer side effects than other anti-inflammatory drugs, such as steroids | UNIVERSITE LAVAL (CA) | 2011-10-18 | — | — | US | disclosed |
| US-20080221085-A1 | Nicotinic Receptor Agonists for the Treatment of Inflammatory Diseases | UNIVERSITE LAVAL (CA) | 2008-09-11 | — | — | US | disclosed |
| EP-1773779-A1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSITE LAVAL (CA) | 2007-04-18 | — | — | EP | disclosed |
| US-RE39088-E1 | Amide compounds and use of the same | JAPAN TOBACCO, INC. (JP) | 2006-05-02 | — | — | US | disclosed |
| WO-2006005195-A1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSITé LAVAL (CA) | 2006-01-19 | — | — | WO | disclosed |
| WO-2005082459-A2 | METHOD OF DECREASING BLOOD CELLS | JAPAN TOBACCO INC. (JP) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187221-A1 | Method of treating ischemia reperfusion injury | JAPAN TOBACCO INC. (JP) | 2005-08-25 | — | — | US | disclosed |
| EP-0849256-B1 | AMIDE COMPOUNDS AND USE OF THE SAME | JAPAN TOBACCO INC (JP) | 2005-06-08 | — | — | EP | disclosed |
| EP-1304322-A2 | Carboxylic acid compound and use thereof | Japan Tobacco Inc. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6420561-B1 | Amide compounds and use thereof | JAPAN TOBACCO INC. (JP) | 2002-07-16 | — | — | US | disclosed |
| US-6174887-B1 | Amide compounds and use of the same | JAPAN TOBACCO INC. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0849256-A1 | AMIDE COMPOUNDS AND USE OF THE SAME | Japan Tobacco Inc. (JP) | 1998-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187221-A1 | Method of treating ischemia reperfusion injury | TNF, IL1B, TNNI3 | MEN1 4862/4885KMT2A 4443/4885SLC22A6 2511/4885 |
| US-20080221085-A1 | Nicotinic Receptor Agonists for the Treatment of Inflammatory Diseases | CHRNA1, CHRNG, CHRM1 | MEN1 3942/4885KMT2A 2948/4885SLC22A6 1644/4885 |
| US-20120022049-A1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | CHRNA1, CHRNG, CHRM1 | MEN1 3942/4885KMT2A 2948/4885SLC22A6 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.