Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772330 | 1.00 | NR4A2 (0.61) | NR4A2SOS2TLR8MAPTGAA | |
| Hydrochloric Acid SCHEMBL1611213 | 0.98 | NR4A2 (0.59) | NR4A2SOS2TLR8MAPTGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL28453203 | 0.84 | NR4A2 (0.46) | NR4A2SOS2TLR8MAPTGAA | |
| SCHEMBL29945144 | 0.84 | NR4A2 (0.61) | NR4A2SOS2TLR8MAPTGAA | |
| SCHEMBL3268768 | 0.84 | NR4A2 (0.61) | NR4A2SOS2TLR8MAPTGAA | |
| SCHEMBL28460490 | 0.80 | ALDH1A1 (0.56) | NR4A2SOS2TLR8MAPTGAA | |
| SCHEMBL29509132 | 0.79 | TLR8 (0.54) | NR4A2SOS2TLR8MAPTGAA | |
| SCHEMBL317202 | 0.79 | NR4A2 (0.66) | NR4A2SOS2TLR8MAPTGAA | |
| SCHEMBL29396540 | 0.79 | NR4A2 (0.66) | NR4A2SOS2TLR8MAPTGAA | |
| SCHEMBL28164080 | 0.79 | TLR8 (0.54) | NR4A2SOS2TLR8MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747890-B | Preparation method of 4, 7-dichloroquinoline | 重庆医药高等专科学校 | 2025-05-09 | — | — | CN | claimed |
| CN-118243807-A | Method for determining piperaquine phosphate related substances | 桂林南药股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118026929-A | Quinoline derivative containing diamine structure, and preparation method and application thereof | 成都理工大学 | 2024-05-14 | — | — | CN | claimed |
| CN-111635358-B | Preparation method of hydroxychloroquine | 北京成宇化工有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-114292232-A | Synthesis and purification method of 4, 7-dichloroquinoline | 南京固与生物有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-111747890-A | Preparation method of 4, 7-dichloroquinoline | 重庆医药高等专科学校 | 2020-10-09 | — | — | CN | claimed |
| CN-111635358-A | Preparation method of hydroxychloroquine | 北京成宇化工有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-111362872-A | Synthetic method of 4, 7-dichloroquinoline | 重庆医药高等专科学校 | 2020-07-03 | — | — | CN | claimed |
| CN-110627716-A | Preparation method of 4, 7-dichloroquinoline | 重庆康乐制药有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-103626699-A | Industrial preparation method of 4,7-dichloroquinoline | WUHAN WUYAO PHARMACEUTICAL CO LTD | 2014-03-12 | — | — | CN | claimed |
| US-20060275666-A1 | an electrode assembly whose top and bottom ends are blocked by a heat sensitive composition to reduce the void volume inside a bare cell during initial overcharge; preventing exploding and ignition; batteries have improved heat resistance | SANSUMG SDI CO., LTD (KR) | 2006-12-07 | — | — | US | claimed |
| CN-1858931-A | Lithium rechargeable battery | SAMSUNG SDI CO LTD (KR) | 2006-11-08 | — | — | CN | claimed |
| US-6673257-B1 | BLENDS EMPLOYING AT LEAST TWO ORGANIC COMPOUNDS HAVING KNOWN MELT TEMPERATURES, EXHIBIT IMPROVED THERMAL PROPERTIES AND PERFORMANCE CHARACTERISTICS | THERM-O-DISC, INCORPORATED | 2004-01-06 | — | — | US | claimed |
| EP-1117647-A1 | METHOD FOR PREPARING 4-HYDROXYQUINOLINES AND/OR TAUTOMERIC FORMS | RHODIA CHIMIE (FR) | 2001-07-25 | — | — | EP | claimed |
| WO-2000018739-A1 | METHOD FOR PREPARING 4-HYDROXYQUINOLINES AND/OR TAUTOMERIC FORMS | RHODIA CHIMIE (FR) | 2000-04-06 | — | — | WO | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0056765-B1 | PREPARATION OF 4-HYDROXYQUINOLINES | RHONE-POULENC SANTE (FR) | 1985-06-19 | — | — | EP | claimed |
| US-4412076-A | Preparation of 4-hydroxyquinolines | RHONE-POULENC SANTE (FR) | 1983-10-25 | — | — | US | claimed |