SCHEMBL4098368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4090661	0.94	PIK3CA (0.57)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4090988	0.91	PSEN1 (0.55)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4110583	0.89	PIK3CA (0.61)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4097260	0.87	PIK3CA (0.56)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4092396	0.86	PSEN1 (0.51)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4098620	0.83	PSEN1 (0.66)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL1039079	0.83	PSEN1 (0.72)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL8006680	0.81	PSEN1 (0.54)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL3412855	0.81	PSEN1 (0.72)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL2359021	0.80	PSEN1 (0.53)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.