Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16314688 | 0.83 | TAAR1 (0.45) | TAAR1IGF1RALOX15HTR3EHTR3B | |
| SCHEMBL11462575 | 0.83 | TAAR1 (0.45) | TAAR1IGF1RALOX15HTR3EHTR3B | |
| SCHEMBL408931 | 0.82 | TAAR1 (0.43) | TAAR1MMP2MMP9MMP12MMP13 | |
| SCHEMBL10247192 | 0.82 | CYP1A2 (0.43) | TAAR1IGF1RALOX15CYP1A2MMP2 | |
| SCHEMBL11180436 | 0.82 | TAAR1 (0.43) | TAAR1IGF1RALOX15HTR3EHTR3B | |
| SCHEMBL14135335 | 0.82 | TAAR1 (0.44) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8371056 | 0.81 | MMP12 (0.49) | CYP2D6MMP2MMP9MMP12MMP13 | |
| SCHEMBL3769347 | 0.81 | MMP12 (0.49) | CYP2D6MMP2MMP9MMP12MMP13 | |
| SCHEMBL11062642 | 0.80 | TAAR1 (0.50) | TAAR1IGF1RALOX15HTR3EHTR3B | |
| SCHEMBL12517335 | 0.80 | MMP12 (0.53) | MMP2MMP9MMP12MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175341-A | Method for industrially synthesizing butoconazole nitrate intermediate | ZHUZHOU QIANJIN PHARMACEUTICAL CO LTD | 2015-12-23 | — | — | CN | claimed |
| JP-4795973-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| CN-101328110-A | Preparation of butoconazole nitrate intermediate | BEIJING D VENTURE PHARM TECH (CN) | 2008-12-24 | — | — | CN | claimed |
| JP-2007519699-A | — | — | 2007-07-19 | — | — | JP | claimed |
| EP-1709005-A1 | HIGH PURITY BUTOCONAZOLE NITRATE WITH SPECIFIED PARTICLE SIZE AND A PROCESS FOR PREPARATION THEREOF | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2006-10-11 | — | — | EP | claimed |
| WO-2005070897-A1 | HIGH PURITY BUTOCONAZOLE NITRATE WITH SPECIFIED PARTICLE SIZE AND A PROCESS FOR PREPARATION THEREOF | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2005-08-04 | — | — | WO | claimed |
| CN-105218455-B | A kind of method for industrializing continuous production Butoconazole Nitrate | 株洲千金药业股份有限公司 | 2018-07-03 | — | — | CN | disclosed |
| CN-105384600-A | Industrial production method for butoconazole nitrate intermediate | ZHUZHOU QIANJIN PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-105198708-A | Method for industrially producing butoconazole nitrate intermediate | ZHUZHOU QIANJIN PHARMACEUTICAL CO LTD | 2015-12-30 | — | — | CN | disclosed |
| CN-105198817-A | Method for industrially synthesizing butoconazole nitrate intermediate | ZHUZHOU QIANJIN PHARMACEUTICAL CO LTD | 2015-12-30 | — | — | CN | disclosed |
| CN-105175341-A | Method for industrially synthesizing butoconazole nitrate intermediate | ZHUZHOU QIANJIN PHARMACEUTICAL CO LTD | 2015-12-23 | — | — | CN | disclosed |
| CN-105175341-A | Method for industrially synthesizing butoconazole nitrate intermediate | ZHUZHOU QIANJIN PHARMACEUTICAL CO LTD | 2015-12-23 | — | — | CN | disclosed |
| CN-103880596-A | Preparation method of butoconazole nitrate intermediate suitable for industrial production | LING PEIXUE | 2014-06-25 | — | — | CN | disclosed |
| EP-0005980-B1 | DERIVATIVES OF SUBSTITUTED N-ALKYL IMIDAZOLES, THEIR PREPARATION AND THESE COMPOUNDS FOR PHARMACEUTICAL USE | SYNTEX (U.S.A.) INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| US-4421758-A | FUNGICIDES | SANKYO COMPANY LIMITED (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4375474-A | BACTERICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1983-03-01 | — | — | US | disclosed |
| EP-0055059-A1 | Diazole and triazole derivatives, processes for their preparation and anti-microbial compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-06-30 | — | — | EP | disclosed |
| US-4272545-A | FUNGICIDES, BACTERICIDE, ANTIPROTOZOA, SPERMATOCIDE | SYNTEX (U.S.A.) INC. (US) | 1981-06-09 | — | — | US | disclosed |
| US-4213991-A | BACTERICIDES, FUNGICIDES, ANTIPROTOZOA | SYNTEX (U.S.A.) INC. (US) | 1980-07-22 | — | — | US | disclosed |
| EP-0005980-A2 | Derivatives of substituted N-alkyl imidazoles, their preparation and these compounds for pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1979-12-12 | — | — | EP | disclosed |