Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | F7 | P08709 | 7/20 | 0.36 |
| ▸ | F3 | P13726 | 7/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099959 | 1.00 | TRPV1 (0.39) | TRPV1ALDH1A1PTGS1MAPTF13A1 | |
| SCHEMBL28730970 | 0.95 | ALDH1A1 (0.39) | TRPV1ALDH1A1PTGS1MAPTPPARG | |
| SCHEMBL29284344 | 0.93 | TRPV1 (0.35) | TRPV1ALDH1A1PTGS1MAPTPPARG | |
| SCHEMBL27874173 | 0.91 | TRPV1 (0.39) | TRPV1ALDH1A1PTGS1MAPTF13A1 | |
| SCHEMBL2551469 | 0.87 | — | — | |
| SCHEMBL2551472 | 0.87 | — | — | |
| SCHEMBL29284232 | 0.86 | ALDH1A1 (0.38) | ALDH1A1PTGS1MAPTPPARGF7 | |
| SCHEMBL29284234 | 0.86 | ALDH1A1 (0.38) | ALDH1A1PTGS1MAPTPPARGF7 | |
| SCHEMBL29284443 | 0.86 | ALDH1A1 (0.38) | ALDH1A1PTGS1MAPTPPARGF7 | |
| SCHEMBL3839180 | 0.85 | TRPV1 (0.44) | TRPV1ALDH1A1PTGS1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061560-A2 | BCL INHIBITORS FOR TREATING PLATELET EXCESS | Abbott Laboratories (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008030836-A2 | BCL INHIBITORS TREATING PLATELET EXCESS | ABBOTT LABORATORIES (US) | 2008-03-13 | — | — | WO | disclosed |