Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093594 | 0.88 | KDM4E (0.48) | KMT2AKDM4EALDH1A1PPP1CASMN1; SMN2 | |
| SCHEMBL21816430 | 0.86 | SMN1; SMN2 (0.58) | KMT2AKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10730944 | 0.81 | KMT2A (0.67) | KMT2APOLBNPY5R | |
| SCHEMBL13901652 | 0.80 | RIPK1 (0.47) | KDM4EALDH1A1MAPTPOLBTRPV1 | |
| SCHEMBL20320330 | 0.79 | SMN1; SMN2 (0.51) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL15362663 | 0.79 | HTT (0.64) | KMT2AKDM4EALDH1A1PPP1CASMN1; SMN2 | |
| SCHEMBL5584120 | 0.74 | KLKB1 (0.69) | KMT2AKDM4EPKMMEN1POLB | |
| SCHEMBL4017916 | 0.74 | SMN1; SMN2 (0.58) | KMT2AKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31522202 | 0.73 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL31175294 | 0.72 | KMT2A (0.73) | KMT2AHTTPOLBTDP1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | KMT2A 3833/4885KDM4E 4055/4885ALDH1A1 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.