SCHEMBL410007

SCHEMBL410007

C=CCOC(=O)C(C)=CCC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 2/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
PTP4A3 O75365 2/20 0.32
PTP4A1 Q93096 2/20 0.32
PTP4A2 Q12974 1/20 0.32
ALDH1A1 P00352 3/20 0.32
HSD17B10 Q99714 2/20 0.32
GLO1 Q04760 1/20 0.31
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050185 1.00 TSHR (0.42) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL10764198 0.85 TSHR (0.43) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL666513 0.84 CYP3A4 (0.40) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL17311783 0.84 TSHR (0.38) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL5696068 0.84 TSHR (0.38) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL5983748 0.84 CYP3A4 (0.40) TSHRCYP3A4CYP2D6CYP2C19TDP1
Ammonia Solution, Strong SCHEMBL7152100 0.82 CYP3A4 (0.39) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL9149500 0.82 TSHR (0.49) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL8971288 0.82 TSHR (0.49) TSHRCYP3A4CYP2D6CYP2C19TDP1
SCHEMBL21377600 0.82 TSHR (0.43) TSHRCYP3A4CYP2D6TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208556-B2 Water-soluble or water-swellable crosslinked copolymers CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-04-24 US claimed
US-20050165188-A1 Water-soluble or water-swellable crosslinked copolymers CLARIANT GMBH 2005-07-28 US claimed
US-6891009-B2 Water-soluble or water-swellable crosslinked copolymers CLARIANT GMBH (DE) 2005-05-10 US claimed
US-6683144-B2 SALTS OF ACRYLAMIDOALKYLSULFONIC ACIDS AND CYCLIC OR LINEAR N-VINYLCARBOXAMIDES MONOMERS WITH CROSSLINKERS HAVING MULTIPLE DOUBLE BONDS; THICKENERS, EMULSION AND DISPERSION STABILLIZERS AND AS GLIDANTS IN COSMETIC AND PHARMACEUTICALS CLARIANT GMBH (DE) 2004-01-27 US claimed
US-6437068-B2 THICKENER FOR COSMETIC, DRUGS CLARIANT GMBH (DE) 2002-08-20 US claimed
US-4396680-A Substrate coated with crater resistant acrylic enamel E. I. DU PONT DE NEMOURS AND CO. (US) 1983-08-02 US claimed
US-4371657-A AMINO RESIN CROSSLINKING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-01 US claimed
JP-63236515-A None JP disclosed
CN-103555119-A Coating for polyolefin membrane as well as modified polyolefin membrane and coating preparation method of coating CHINA HAISUM ENG CO LTD 2014-02-05 CN disclosed
EP-1664222-B1 METHOD FOR ACHIEVING RECOAT ADHESION OVER A FLUORINATED TOPCOAT DU PONT (US) 2012-01-25 EP disclosed
EP-2015858-B1 NONWOVEN WEB OF POLYMER-COATED NANOFIBERS DU PONT (US) 2011-09-14 EP disclosed
US-20100136865-A1 Nonwoven web of polymer-coated nanofibers E. I. DU PONT DE NEMOURS AND COMPANY 2010-06-03 US disclosed
US-7704606-B2 Method for achieving recoat adhesion over a fluorinated topcoat E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-27 US disclosed
JP-S63236515-A GAS SEPARATING MEMBRANE MITSUBISHI PAPER MILLS LTD 1988-10-03 JP disclosed
US-4396680-A Substrate coated with crater resistant acrylic enamel E. I. DU PONT DE NEMOURS AND CO. (US) 1983-08-02 US disclosed
US-4371657-A AMINO RESIN CROSSLINKING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-01 US disclosed
US-4000327-A BERRY FRUIT FOODSTUFFS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-12-28 US disclosed
US-3998873-A ORGANOLEPTICS, PERFUMES, AROMAS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-12-21 US disclosed
US-3984579-A Novel flavoring compositions and products containing isomer mixtures containing high proportions of 2-methyl-cis-3-pentenoic acid INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-05 US disclosed
US-3931293-A Processes for producing cis alkyl-2-methyl-3-pentenoates and isomer mixtures containing high proportions of cis alkyl-2-methyl-3-pentenoates INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-01-06 US disclosed