Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.35 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.35 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666513 | 1.00 | CYP3A4 (0.40) | CYP3A4TSHRALDH1A1HSD17B10TDP1 | |
| Ammonia Solution, Strong SCHEMBL7152100 | 0.98 | CYP3A4 (0.39) | CYP3A4TSHRALDH1A1HSD17B10TDP1 | |
| Succinic Acid SCHEMBL28371751 | 0.91 | TSHR (0.37) | CYP3A4TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL6050185 | 0.84 | TSHR (0.42) | CYP3A4TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL5696068 | 0.84 | TSHR (0.38) | CYP3A4TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL17311783 | 0.84 | TSHR (0.38) | CYP3A4TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL410007 | 0.84 | TSHR (0.42) | CYP3A4TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL410006 | 0.84 | CYP2D6 (0.45) | TSHRALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL28797840 | 0.84 | CYP2D6 (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL29409561 | 0.83 | TSHR (0.37) | CYP3A4TSHRALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139687-A1 | SOOT DISPERSANT COMPRISING BLOCK COPOLYMER AND LUBRICANT COMPOSITION CONTAINING THE SAME | CRODA SINGAPORE PTE LIMITED (SG) | 2022-06-30 | — | — | WO | disclosed |
| EP-1570837-B1 | DENDRITE ELONGATION INHIBITOR FOR MELANOCYTE AND SKIN PREPARATION FOR EXTERNAL USE CONTAINING THE SAME | POLA CHEM IND INC (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-7141601-B2 | Dendrite elongation inhibitor for melanocyte and skin preparation for external use containing the same | POLA CHEMIOCAL INDUSTRIES INC. (JP) | 2006-11-28 | — | — | US | disclosed |
| US-20050288361-A1 | Dendrite elongation inhibitor for melanocyte and skin preparation for external use containing the same | POLA CHEMICAL INDUSTRIES INC. (JP) | 2005-12-29 | — | — | US | disclosed |
| EP-1570837-A1 | DENDRITE ELONGATION INHIBITOR FOR MELANOCYTE AND SKIN PREPARATION FOR EXTERNAL USE CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2005-09-07 | — | — | EP | disclosed |
| EP-1570838-A1 | DENDRITE ELONGATION INHIBITOR FOR MELANOCYTE AND SKIN PREPARATION FOR EXTERNAL USE CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2005-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288361-A1 | Dendrite elongation inhibitor for melanocyte and skin preparation for external use containing the same | TYR, MAP2, KRT18 | CYP3A4 4827/4885TSHR 2450/4885ALDH1A1 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.