⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094766 | 0.93 | EPHX1 (0.48) | — | |
| SCHEMBL9973238 | 0.91 | EPHX1 (0.52) | — | |
| SCHEMBL4098965 | 0.91 | EPHX1 (0.52) | — | |
| SCHEMBL4094668 | 0.91 | EPHX1 (0.52) | — | |
| SCHEMBL4109571 | 0.91 | EPHX1 (0.52) | — | |
| SCHEMBL2905605 | 0.91 | EPHX1 (0.52) | — | |
| SCHEMBL13227081 | 0.89 | EPHX1 (0.39) | — | |
| SCHEMBL1276675 | 0.87 | EPHX1 (0.48) | — | |
| SCHEMBL4100814 | 0.84 | — | — | |
| SCHEMBL4104968 | 0.83 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355705-A1 | DISCOVERY OF YEATS2 YEATS DOMAIN INHIBITORS AS NOVEL ANTI-CANCER AGENTS | THE UNIVERSITY OF HONG KONG (CN) | 2023-11-09 | — | — | US | disclosed |
| WO-2023005945-A1 | CYCLIC PEPTIDE, PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州彗搏科技有限公司 | 2023-02-02 | — | — | WO | disclosed |
| US-20200316159-A1 | SUSTAINED RELEASE COMPOSITIONS OF KAPPA-OPIOID RECEPTOR AGONIST | TITAN PHARMACEUTICALS, INC. | 2020-10-08 | — | — | US | disclosed |
| EP-2755690-B1 | KISSPEPTIDE-PENTASACCHARIDE CONJUGATES | MERCK SHARP & DOHME (NL) | 2020-04-01 | — | — | EP | disclosed |
| WO-2017210668-A1 | SUSTAINED RELEASE COMPOSITIONS OF KAPPA-OPIOID RECEPTOR AGONIST | JT PHARMACEUTICALS, INC. (US) | 2017-12-07 | — | — | WO | disclosed |
| US-9669038-B1 | Heterocyclic compounds and uses thereof | GLOBAVIR BIOSCIENCES, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-9321749-B1 | Heterocyclic compounds and uses thereof | GLOBAVIR BIOSCIENCES, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-9221841-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150191490-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20140018399-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20080009504-A1 | Antifungal agents | SCYNEXIS, INC. | 2008-01-10 | — | — | US | disclosed |
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |
| EP-1826200-A2 | Oxime derivative, photopolymerisable composition, colour filter and process for producing the same | FUJIFILM Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006110185-A2 | ANTIINFECTIVE LIPOPEPTIDES | CUBIST PHARMACEUTICALS, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |