Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4098965 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL2905605 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL4109571 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL9973238 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL4094668 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL4100608 | 0.93 | — | — | |
| SCHEMBL14868287 | 0.89 | EPHX1 (0.43) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL88539 | 0.87 | EPHX1 (0.54) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL9973239 | 0.87 | EPHX1 (0.47) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| Hydrochloric Acid SCHEMBL1938197 | 0.86 | EPHX1 (0.45) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669038-B1 | Heterocyclic compounds and uses thereof | GLOBAVIR BIOSCIENCES, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-9321749-B1 | Heterocyclic compounds and uses thereof | GLOBAVIR BIOSCIENCES, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8268871-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100331283-A1 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-7329402-B2 | Methods of imaging and treatment | IMARX PHARMACEUTICAL CORP. (US) | 2008-02-12 | — | — | US | disclosed |
| WO-2008010043-A2 | IMPROVED PROCESS FOR THE PREPARATION OF CEFORANIDE IN PURE FORM | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| US-4659814-A | Salts of amino-beta-lactamic acids and process for the preparation thereof | GEMA, S.A. (ES) | 1987-04-21 | — | — | US | disclosed |
| EP-0127541-A2 | Salts of amino-beta-lactamic acids and process for the preparation thereof | GEMA S.A. (ES) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | EPHX1 3319/4885CASP2 4367/4885ALDH1A1 1963/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | EPHX1 2311/4885CASP2 3271/4885ALDH1A1 1279/4885 |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | KIF5B, KIF2C, KIF18B | EPHX1 3193/4885CASP2 3758/4885ALDH1A1 2961/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | EPHX1 2359/4885CASP2 4409/4885ALDH1A1 1073/4885 |
| US-20100331283-A1 | Mitotic kinesin inhibitors and methods of use thereof | KIF5B, KIF2C, KIFC1 | EPHX1 3232/4885CASP2 3419/4885ALDH1A1 2827/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | EPHX1 3675/4885CASP2 4303/4885ALDH1A1 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.