Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | FABP6 | P51161 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4115801 | 0.91 | GRIN1 (0.53) | ABL1FABP6ALDH1A1HPGDKDR | |
| SCHEMBL8214601 | 0.89 | PLAU (0.43) | ABL1FABP6ACP1ALDH1A1KDM4E | |
| SCHEMBL4108132 | 0.89 | HTR3E (0.54) | ABL1FABP6ALDH1A1KDM4EMEN1 | |
| SCHEMBL4115769 | 0.89 | KDR (0.46) | ABL1FABP6ACP1MEN1KMT2A | |
| SCHEMBL12313735 | 0.89 | KDR (0.46) | ABL1FABP6ACP1MEN1KMT2A | |
| SCHEMBL4113010 | 0.89 | EGFR (0.48) | ABL1FABP6ALDH1A1KDM4EMEN1 | |
| SCHEMBL4123591 | 0.88 | ACP1 (0.48) | ABL1FABP6ACP1ALDH1A1KDM4E | |
| SCHEMBL335832 | 0.88 | ACP1 (0.48) | ABL1FABP6ACP1ALDH1A1KDM4E | |
| SCHEMBL4109421 | 0.88 | ACP1 (0.48) | ABL1FABP6ACP1ALDH1A1KDM4E | |
| SCHEMBL4113916 | 0.87 | NR2E3 (0.45) | ABL1FABP6ACP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069288-B1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS | SANOFI SA (FR) | 2014-03-26 | — | — | EP | claimed |
| US-8263621-B2 | Tartrate derivatives for use as coagulation factor IXa inhibitors | SANOFI (FR) | 2012-09-11 | — | — | US | claimed |
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | claimed |
| EP-2069288-B1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS | SANOFI SA (FR) | 2014-03-26 | — | — | EP | disclosed |
| US-8263621-B2 | Tartrate derivatives for use as coagulation factor IXa inhibitors | SANOFI (FR) | 2012-09-11 | — | — | US | disclosed |
| US-8263621-B2 | Tartrate derivatives for use as coagulation factor IXa inhibitors | SANOFI (FR) | 2012-09-11 | — | — | US | disclosed |
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | disclosed |
| WO-2008031508-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXa INHIBITORS | SANOFI-AVENTIS (FR) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | TFPI, TFPI2, F9 | ABL1 1021/4885FABP6 2884/4885ACP1 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.