Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.43 |
| ▸ | MICA | Q29983 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847465 | 0.85 | CHRM3 (0.43) | CHRM3EPHX2EPHX1C3AR1 | |
| SCHEMBL4955085 | 0.85 | CHRM3 (0.43) | CHRM3EPHX2EPHX1C3AR1 | |
| SCHEMBL4758293 | 0.84 | CHRM3 (0.47) | CHRM3C3AR1CNR1 | |
| SCHEMBL3960883 | 0.84 | SLC6A2 (0.45) | TEAD1EPHX2EPHX1KLRK1MICA | |
| SCHEMBL3954625 | 0.84 | SLC6A2 (0.45) | TEAD1EPHX2EPHX1KLRK1MICA | |
| SCHEMBL4847784 | 0.81 | CHRM3 (0.42) | CHRM3EPHX2EPHX1 | |
| SCHEMBL4117389 | 0.81 | CHRM3 (0.42) | CHRM3EPHX2EPHX1 | |
| SCHEMBL3986502 | 0.78 | CHRM3 (0.52) | CHRM3EPHX2EPHX1LMNAC3AR1 | |
| SCHEMBL3992224 | 0.78 | CHRM3 (0.52) | CHRM3EPHX2EPHX1LMNAC3AR1 | |
| SCHEMBL3954725 | 0.77 | SLC6A2 (0.46) | EPHX2KLRK1MICALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550485-B2 | Substituted N-heterocycle derivatives and methods of their use | WYETH (US) | 2009-06-23 | — | — | US | disclosed |