Aceroside B1

Aceroside B1

SCHEMBL4101421

OC[C@H]1O[C@H](Oc2ccc3cc2Oc2ccc(cc2)CCCC[C@@H](O)CC3)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.49
NFKB2 Q00653 2/20 0.49
RELA Q04206 2/20 0.49
ACHE P22303 1/20 0.43
ATM Q13315 1/20 0.39
TYR P14679 1/20 0.39
PTGS1 P23219 1/20 0.38
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
SLC28A3 Q9HAS3 1/20 0.38
SLC5A2 P31639 2/20 0.38
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
SLC5A1 P13866 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aceroside I SCHEMBL13698044 1.00 NFKB1 (0.49) NFKB1NFKB2RELAACHEATM
Aceroside I SCHEMBL15996716 1.00 NFKB1 (0.49) NFKB1NFKB2RELAACHEATM
Aceroside I SCHEMBL15996710 1.00 NFKB1 (0.49) NFKB1NFKB2RELAACHEATM
Aceroside B1 SCHEMBL15996711 1.00 NFKB1 (0.49) NFKB1NFKB2RELAACHEATM
Aceroside B1 SCHEMBL13698046 1.00 NFKB1 (0.49) NFKB1NFKB2RELAACHEATM
SCHEMBL13698112 0.87 NFKB1 (0.55) NFKB1NFKB2RELAACHE
SCHEMBL10048264 0.87 NFKB1 (0.55) NFKB1NFKB2RELAACHE
SCHEMBL13698111 0.87 NFKB1 (0.55) NFKB1NFKB2RELAACHE
SCHEMBL15996705 0.86 NFKB1 (0.40) NFKB1NFKB2RELAACHELMNA
SCHEMBL13698048 0.86 NFKB1 (0.40) NFKB1NFKB2RELAACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822705-B2 Pharmaceutical composition for preventing and/or treating bone disease, functional food or health food and pharmaceutical preparation comprising thereof as active ingredient Akihisa, Toshihiro (JP) 2014-09-02 US disclosed
US-20090227527-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING BONE DISEASE, FUNCTIONAL FOOD OR HEALTH FOOD AND PHARMACEUTICAL PREPARATION COMPRISING THEREOF AS ACTIVE INGREDIENT Akihisa, Toshihiro (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227527-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING BONE DISEASE, FUNCTIONAL FOOD OR HEALTH FOOD AND PHARMACEUTICAL PREPARATION COMPRISING THEREOF AS ACTIVE INGREDIENT HRH1, HRH2, HRH3 NFKB1 388/4885NFKB2 1238/4885RELA 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.