SCHEMBL4101586

SCHEMBL4101586

NNC1=NCCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL1545196 0.98
Hydrochloric Acid SCHEMBL11683033 0.98
Hydrochloric Acid SCHEMBL11299112 0.98 NOS3 (0.48)
Bromide SCHEMBL6285325 0.98
SCHEMBL8781427 0.93
Iodide SCHEMBL11150641 0.91 NOS3 (0.41)
Hydrochloric Acid SCHEMBL11687689 0.91 NOS3 (0.41)
Hydrochloric Acid SCHEMBL11685765 0.91 NOS3 (0.41)
Bromide SCHEMBL11701958 0.89 NOS3 (0.40)
Bromide SCHEMBL11702626 0.89 NOS3 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4374135-A AMIDINO HYDRAZONE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1983-02-15 US claimed
US-4213988-A Insecticidal 1,5-bis(α,α,α-trifluoro-p-tolyl)-1,4-pentadien-3-one (1,4,5,6-tetrahydro-2-pyrimidinyl)hydrazones AMERICAN CYANAMID COMPANY (US) 1980-07-22 US claimed
US-4163102-A INSECTICIDES AMERICAN CYANAMID CO. (US) 1979-07-31 US claimed
US-4006234-A Substituted 2-benzofuranyl propenones as anti-tubercular agents AMERICAN CYANAMID COMPANY (US) 1977-02-01 US claimed
US-3931157-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US claimed
EP-3265448-B1 RILUZOLE PRODRUGS AND THEIR USE BIOHAVEN PHARM HOLDING CO LTD (US) 2021-12-29 EP disclosed
CN-102276593-A Heterocyclic ketene hydrazone compound and preparation method as well as tubercle bacillus resistant application 2011-12-14 CN disclosed
US-20090194124-A1 Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine MALLE GERARD 2009-08-06 US disclosed
US-20090139537-A1 HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE L'OREAL S.A. 2009-06-04 US disclosed
EP-1017680-B1 TRICYCLIC COMPOUNDS, PREPARATION METHOD AND SAID METHOD INTERMEDIATES, APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AVENTIS PHARMA SA (FR) 2007-02-07 EP disclosed
US-20050136017-A1 Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin L'OREAL S.A. (FR) 2005-06-23 US disclosed
US-20050129645-A1 Hair shaping composition comprising at least one non-hydroxide imine L'OREAL 2005-06-16 US disclosed
US-4213988-A Insecticidal 1,5-bis(α,α,α-trifluoro-p-tolyl)-1,4-pentadien-3-one (1,4,5,6-tetrahydro-2-pyrimidinyl)hydrazones AMERICAN CYANAMID COMPANY (US) 1980-07-22 US disclosed
US-4191768-A Pentadienone hydrazones, method for preparing the same, and insecticidal use thereof AMERICAN CYANAMID COMPANY (US) 1980-03-04 US disclosed
US-4163102-A INSECTICIDES AMERICAN CYANAMID CO. (US) 1979-07-31 US disclosed
US-4163102-A INSECTICIDES AMERICAN CYANAMID CO. (US) 1979-07-31 US disclosed
US-RE29358-E ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS AMERICAN CYANAMID COMPANY (US) 1977-08-16 US disclosed
US-4006234-A Substituted 2-benzofuranyl propenones as anti-tubercular agents AMERICAN CYANAMID COMPANY (US) 1977-02-01 US disclosed
US-3931152-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US disclosed
US-3931157-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US disclosed