Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.88 |
| ▸ | F3 | P13726 | 1/20 | 0.88 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.88 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.88 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.88 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.88 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.88 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.88 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.58 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL28744959 | 0.96 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL18443774 | 0.94 | F7 (0.85) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28307211 | 0.94 | F7 (0.85) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL5712652 | 0.94 | F7 (0.92) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL27671762 | 0.94 | F7 (0.92) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL2926 | 0.94 | — | — | |
| Niacinamide SCHEMBL19978192 | 0.94 | — | — | |
| Niacinamide SCHEMBL29624874 | 0.94 | — | — | |
| Niacinamide SCHEMBL460466 | 0.94 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL20298468 | 0.92 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572710-A | Method for serum-free hypoxia culture of mesenchymal stem cells | 内蒙古蒙科干细胞基因医学研究有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115572710-A | Method for serum-free hypoxia culture of mesenchymal stem cells | 内蒙古蒙科干细胞基因医学研究有限公司 | 2023-01-06 | — | — | CN | disclosed |
| US-20090111759-A1 | Synergistic Combination of Glutamate-and Gaba-Gated Chloride Agonist Pesticide and at Least One Vitamin E, Niacin, or Derivatives Thereof | CHEMINOVA A/S (DK) | 2009-04-30 | — | — | US | disclosed |
| EP-1998621-A2 | SYNERGISTIC COMBINATION OF GLUTAMATE- AND GABA-GATED CHLORIDE AGONIST PESTICIDE AND AT LEAST ONE OF VITAMIN E, NIACIN, OR DERIVATIVES THEREOF | Cheminova A/S (DK) | 2008-12-10 | — | — | EP | disclosed |
| EP-1849363-A1 | Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin | Cheminova A/S (DK) | 2007-10-31 | — | — | EP | disclosed |
| WO-2007101447-A2 | SYNERGISTIC COMBINATION OF GLUTAMATE-AND GABA-GATED CHLORIDE AGONIST PESTICIDE AND AT LEAST ONE OF VITAMIN E, NIACIN, OR DERIVATIVES THEREOF | CHEMINOVA A/S (DK) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111759-A1 | Synergistic Combination of Glutamate-and Gaba-Gated Chloride Agonist Pesticide and at Least One Vitamin E, Niacin, or Derivatives Thereof | SLC6A1, GABRE, GRIN1 | F7 3785/4885F3 4618/4885SARM1 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.