Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.64 |
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.57 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13774777 | 1.00 | DGAT1 (0.64) | DGAT1CYP24A1CYP26A1CYP27A1CYP19A1 | |
| SCHEMBL4621871 | 0.90 | CYP24A1 (0.68) | DGAT1CYP24A1CYP26A1CYP27A1CYP19A1 | |
| SCHEMBL4096787 | 0.86 | CYP24A1 (0.50) | DGAT1CYP24A1CYP26A1CYP27A1CYP19A1 | |
| SCHEMBL13774776 | 0.86 | CYP24A1 (0.50) | DGAT1CYP24A1CYP26A1CYP27A1CYP19A1 | |
| SCHEMBL7295884 | 0.83 | CYP19A1 (0.65) | CYP24A1CYP26A1CYP27A1CYP19A1ITGB3 | |
| SCHEMBL9855296 | 0.79 | CYP24A1 (0.63) | CYP24A1CYP26A1CYP27A1CYP19A1ITGB3 | |
| SCHEMBL14060281 | 0.79 | DGAT1 (0.84) | DGAT1ITGB3ITGA2B | |
| SCHEMBL8536553 | 0.78 | DGAT1 (0.57) | DGAT1CYP24A1CYP26A1CYP27A1CYP19A1 | |
| SCHEMBL14061883 | 0.78 | DGAT1 (1.00) | DGAT1CYP26A1ITGB3ITGA2B | |
| SCHEMBL4621209 | 0.78 | CYP24A1 (0.65) | CYP24A1CYP26A1CYP27A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | DGAT1 1072/4885CYP24A1 50/4885CYP26A1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.