SCHEMBL410205

SCHEMBL410205

CC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
POLB P06746 1/20 0.55
FABP5 Q01469 3/20 0.54
FABP7 O15540 2/20 0.54
EPHX2 P34913 1/20 0.51
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CASP3 P42574 2/20 0.45
ALDH1A1 P00352 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29608029 1.00 KMT2A (0.55) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL10119030 0.88 KMT2A (0.51) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL16070810 0.88 EPHX2 (0.49) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL13826222 0.87 KMT2A (0.48) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL20759187 0.87 EPHX2 (0.45) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL20759381 0.87 FABP5 (0.45) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL29703842 0.86 KMT2A (0.47) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL17742679 0.85 POLB (0.44) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL15981181 0.85 KMT2A (0.58) KMT2APOLBFABP5FABP7EPHX2
SCHEMBL44676 0.85 KMT2A (0.58) KMT2APOLBFABP5FABP7EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2236 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151672-A1 DIRECTED BIOSYNTHESIS OF MODIFIED ANTHRAQUINONE-FUSED ENEDIYNES AS POTENTIAL CANCER THERAPEUTICS THE JOHNS HOPKINS UNIVERSITY (US) 2024-07-18 WO disclosed
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 US disclosed
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 US disclosed
US-12037357-B2 Compounds for activating invariant natural killer T-cells and methods of use in eliminating inflammatory senescent cells DECIDUOUS THERAPEUTICS, INC. (US) 2024-07-16 US disclosed
WO-2024145273-A2 N-MYRISTOYLTRANSFERASE INHIBITORS AND METHODS OF USE SEATTLE CHILDREN'S HOSPITAL (D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE) (US) 2024-07-04 WO disclosed
WO-2024137502-A2 PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2024-06-27 WO disclosed
US-20240209363-A1 OLIGONUCLEOTIDES FOR TREATING EXPANDED REPEAT DISEASES JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2024-06-27 US disclosed
EP-3488870-B1 ANTI-CD70 ANTIBODY DRUG CONJUGATES AMBRX INC (US) 2024-03-20 EP disclosed
US-20240067674-A1 METHOD FOR LOADING AMINO ACID ON RESIN FOR SOLID-PHASE SYNTHESIS CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-02-29 US disclosed
US-11911403-B2 Antisense-induced exon exclusion in type VII collagen SAREPTA THERAPEUTICS, INC. (US) 2024-02-27 US disclosed
WO-2004094461-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-11-04 WO disclosed
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders ARBOGAST CHRISTOPHE (FR) 2004-10-21 US disclosed
WO-2003033671-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-24 WO disclosed
US-6359113-B1 USING FUSED RING SYSTEM CONTAINING AT LEAST 4 AROMATIC RINGS, AND GROUP CONTAINING AT LEAST ONE CARBON ATOM WHICH IS CAPABLE OF BONDING TO A GROUP TO BE PROTECTED; SYNTHESIS, SEPARATION RHODIA CHIMIE (FR) 2002-03-19 US disclosed
EP-0920403-B1 PROCESS FOR PREPARING CYCLOPENTADIENYL COMPOUNDS BASELL TECHNOLOGY CO BV (NL) 2002-01-30 EP disclosed
US-6162937-A Process for preparing cyclopentadienyl compounds MONTELL TECHNOLOGY COMPANY B.V. (NL) 2000-12-19 US disclosed
CN-1226882-A Process for preparing cyclopentadienyl compounds MONTELL TECHNOLOGY COMPANY BV (NL) 1999-08-25 CN disclosed
EP-0920403-A1 PROCESS FOR PREPARING CYCLOPENTADIENYL COMPOUNDS Montell Technology Company bv (NL) 1999-06-09 EP disclosed
US-5869605-A Protected compound comprising a protective group removably attached to a compound to be protected RHONE-POULENCCHIMIE (FR) 1999-02-09 US disclosed
WO-1998043931-A1 PROCESS FOR PREPARING CYCLOPENTADIENYL COMPOUNDS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1998-10-08 WO disclosed