SCHEMBL15981181

SCHEMBL15981181

O=C(OCC1c2ccccc2-c2ccccc21)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.58
FABP5 Q01469 3/20 0.56
FABP7 O15540 2/20 0.56
EPHX2 P34913 1/20 0.54
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
HTR2A P28223 1/20 0.47
POLB P06746 1/20 0.44
CASP3 P42574 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10405601 0.91 FABP5 (0.56) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL30253705 0.90 FABP5 (0.52) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL28347737 0.89 KMT2A (0.52) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL31572314 0.89 KMT2A (0.52) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL4906918 0.88 KMT2A (0.52) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL44676 0.88 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL28384837 0.88 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL3630096 0.87 KMT2A (0.48) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL4728768 0.87 KMT2A (0.48) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL2782675 0.86 KMT2A (0.56) KMT2AFABP5FABP7EPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141981-A1 NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS Shanghai MICURX Pharmaceuticals Co., Ltd. (CN) 2023-05-11 US disclosed
US-20140238939-A1 IMMOBILIZATION OF ANTIMICROBIAL POLYMERS ON RO MEMBRANE TO REDUCE BIOFILM GROWTH AND BIOFOULING WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141981-A1 NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS GLS, ATP6V1B1, KRAS KMT2A 2683/4885FABP5 629/4885FABP7 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.